| Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block] |
| |
|
2025 |
|
|
2024 |
|
| |
|
|
|
|
|
|
|
|
| Domestic |
|
$ |
(17,100,959 |
) |
|
$ |
(34,984,213 |
) |
| Foreign |
|
|
1,419,702 |
|
|
|
(275,725 |
) |
| Total |
|
$ |
(15,681,257 |
) |
|
$ |
(35,259,938 |
) |
|
| Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] |
| |
|
2025 |
|
|
2024 |
|
| |
|
Amount |
|
|
Tax Rate |
|
|
Amount |
|
|
Tax Rate |
|
| Income tax benefit at U.S. federal statutory rates |
|
$ |
(3,293,064 |
) |
|
|
21.0 |
% |
|
$ |
(7,404,587 |
) |
|
|
21.0 |
% |
| State income tax benefit, net of federal benefits |
|
|
(517,481 |
) |
|
|
3.3 |
|
|
|
(573,327 |
) |
|
|
1.6 |
|
| Non-deductible expenses |
|
|
130,606 |
|
|
|
(0.8 |
) |
|
|
3,192 |
|
|
|
0.0 |
|
| U.S. research and development tax credit |
|
|
(563,811 |
) |
|
|
3.6 |
|
|
|
655,526 |
|
|
|
(1.9 |
) |
| Effect of change in effective tax rate |
|
|
(1,923,131 |
) |
|
|
12.3 |
|
|
|
— |
|
|
|
— |
|
| Change in valuation allowance |
|
|
7,085,656 |
|
|
|
(45.2 |
) |
|
|
7,214,966 |
|
|
|
(20.5 |
) |
| Other, net |
|
|
(918,775 |
) |
|
|
5.8 |
|
|
|
104,230 |
|
|
|
(0.2 |
) |
| Income tax expense |
|
$ |
— |
|
|
|
— |
% |
|
$ |
— |
|
|
|
— |
% |
|
| Schedule of Deferred Tax Assets and Liabilities [Table Text Block] |
| |
|
2025 |
|
|
2024 |
|
| Deferred tax assets: |
|
|
|
|
|
|
|
|
| Federal net operating loss carryforwards |
|
$ |
33,977,118 |
|
|
$ |
34,485,560 |
|
| State net operating loss carryforwards |
|
|
4,821,234 |
|
|
|
3,662,406 |
|
| Foreign net operating loss carryforwards – U.K. |
|
|
3,153,044 |
|
|
|
3,510,437 |
|
| Research and development tax credit carryforward |
|
|
8,211,696 |
|
|
|
7,647,885 |
|
| Research and development expense |
|
|
11,276,599 |
|
|
|
8,969,277 |
|
| Accrued compensation |
|
|
852,988 |
|
|
|
911,277 |
|
| Share-based compensation |
|
|
12,735,324 |
|
|
|
10,198,368 |
|
| Interest expense |
|
|
2,220,525 |
|
|
|
2,241,652 |
|
| Credit loss provision |
|
|
951,057 |
|
|
|
885,562 |
|
| Other, net – U.S. |
|
|
412,013 |
|
|
|
385,414 |
|
| Gross deferred tax assets |
|
|
78,611,598 |
|
|
|
72,897,838 |
|
| Valuation allowance for deferred tax assets |
|
|
(78,611,598 |
) |
|
|
(72,502,102 |
) |
| Net deferred tax assets |
|
|
— |
|
|
|
395,736 |
|
| Deferred tax liabilities: |
|
|
|
|
|
|
|
|
| Change in fair value of derivative liability |
|
|
— |
|
|
|
(395,736 |
) |
| Net deferred tax liabilities |
|
|
— |
|
|
|
(395,736 |
) |
| Net deferred tax asset |
|
$ |
— |
|
|
$ |
— |
|
|